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Article: Studies from University of Pittsburgh have provided new data on neuroinflammation.
- Article from:
- Biotech Week
- Article date:
- October 22, 2008
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Current study results from the report, 'The positron emission tomography ligand DAA1106 binds with high affinity to activated microglia in human neurological disorders,' have been published. "Chronic microglial activation is an important component of many neurological disorders, and imaging activated microglia in vivo will enable the detection and improved treatment of neuroinflammation. 1-(2-chlorphenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinoline-carbox-amide (PK11195), a peripheral benzodiazepine receptor ligand, has been used to image neuroinflammation, but the extent to which PK11195 binding distinguishes activated microglia and reactive astrocytes is unclear. ...