Article: Molecular diagnosis of inherited disease.

As the list of known heritable gene disorders grows, advanced research techniques such as PCR reverse dot blot and the protein truncation test are bolstering the role of molecular biology in genetic testing and counseling.

In the past decade, there has been an exponential increase in the amount of information available about the human genome. The Human Genome Project has increased our understanding of the architecture of the human genome and facilitated the development of molecular biology techniques. Together, these advances have led to the determination of the molecular basis of many diseases.

Currently, the best understood are the single gene disorders, in ...

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