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Article: Resveratrol: Thousands of Bottles of Wine, High-Dose Pills Not Required.
- Article from:
- BIOTECH Patent News
- Article date:
- May 1, 2008
CopyrightCOPYRIGHT 2008 Biotech Patent News. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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While an earlier published rodent study showed that ultra-high doses of resveratrol (1565 milligram human dose - equivalent to 1500 bottles of wine or many dietary supplement capsules) successfully overcame the adverse effects of a high-fat diet, the lowest dose that genetically mimics a calorie restricted diet was, until now, undetermined.
An authoritative gene array study, conducted by researchers at the William S. Middleton Memorial Veterans Hospital and Lifegen Technologies (Madison, WI), shows that a dose of resveratrol (rez-vair-aw-trawl) ~343 milligrams per day (4.9 mg per kilogram of body weight) produces a gene activation profile similar to a calorie ...