Article: Weight loss critical in diabetes management.(IN THE NEWS)(Brief article)(Clinical report)

Overweight patients with type 2 diabetes should lose weight, rather than take ever-increasing doses of insulin, according to diabetes researcher, Roger H. Unger, MD.

In a commentary that appeared recently in the Journal of the American Medical Association, (1) Dr. Unger noted that the current paradigm regarding type 2 diabetes focuses on patients' high blood sugar levels, and involves treatments designed to reduce blood sugar, often through intensive insulin therapy. But insulin resistance and the failure of pancreatic beta cells to produce adequate insulin are the result of lipotoxicity, or fatty acid poisoning, according to a new view of the disease. (2)

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