Article: Tumor volume in subcutaneous mouse xenografts measured by microCT is more accurate and reproducible than determined by .sup.18.sup.F-FDG-microPET or external caliper.(Research article)(Report)

Authors: Mette Munk Jensen [1,2]; Jesper Tranekjaer J ørgensen [1,2]; Tina Binderup [1,2]; Andreas Kjaer (corresponding author) [1,2]

Background

Measurement of tumor size is important in preclinical animal studies when assessing responses to cancer treatment. In longitudinal studies, sequential measurements of tumor volume with a non-invasive method are essential. Current standard technique for volume determination of subcutaneously xenografted tumors in vivo

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