Article: Immune response to allergens in sheep sensitized to house dust mite.(Research)(Report)

Authors: Robert J Bischof (corresponding author) [1]; Ken J Snibson [2]; Joanne Van Der Velden [2]; Els NT Meeusen [1]

Background

Many proteins of the house dust mite (HDM) Dermatophagoides pteronyssinus are potent enzymes and represent the most important allergens associated with human allergic asthma [1]. The most extensively studied HDM allergens are Der p 1 and Der p 2 and it has been shown that the majority of HDM-sensitized asthmatic patients (80-100%) have strong serum IgE responses to these allergens [2].

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