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Article: Platelet function testing.
- Article from:
- Journal of Continuing Education Topics & Issues
- Article date:
- August 1, 2008
- Author:
CopyrightCOPYRIGHT 2008 American Medical Technologists. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Platelets
Platelets or thrombocytes are small cells that are vital in the blood clotting process. Platelets are produced in the bone marrow and circulate in the blood until they are activated by collagen, thrombin, ADP receptors (P2Y1 and P2Y12) expressed on platelets, a negatively charged surface as well as many other activating factors." They are rapidly deployed to injury or infection sites and potentially modulate inflammatory processes by interacting with leukocytes and secreting cytokines and chemokines. (3)
Platelet Function
When there is an injury to a blood vessel, the circulating platelets will adhere to the injury site, aggregate ...