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Article: New chromatography study findings have been reported by S.G. Delyle and colleagues.(Report)

Article from:
Obesity & Diabetes Week
Article date:
October 27, 2008
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New investigation results, 'Determination of rimonabant in human plasma and hair by liquid chromatography-mass spectrometry,' are detailed in a study published in Journal of Chromatography B. "Rimonabant is the first therapeutically relevant cannabinoid antagonist, licensed in Europe for treatment of obesity when a risk factor is associated. The objective of this study was to develop and validate a method for measurement of rimonabant in human plasma and hair using liquid chromatography coupled to mass spectrometry (LC-MS/MS)," scientists in Garches, France report (see also Chromatography).

"Rimonabant and AM-251 (internal standard) were extracted from 50 microL ...

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