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Article: Research from L.H. Zhang and co-researchers in the area of Alzheimer disease described.
- Article from:
- Biotech Week
- Article date:
- November 5, 2008
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"The pathological key features of Alzheimer's disease (AD) are beta-amyloid peptide (A beta)-containing senile plaques (SP) and neurofibrillary tangles. Previous studies have suggested that an extracellular elevation of the zinc concentration can initiate the deposition of A beta and lead to the formation of SP," scientists writing in the journal Brain Research Bulletin report (see also Alzheimer Disease).
"In the present study, we present data showing a correlation between zinc ions, zinc transporters (ZNTs) and AD, using immersion auto metallography (AMG) and double immunofluorescence for the ZNTs and A beta. We found that all the ZNTs tested (ZNT1, 3,4,5,6, 7) ...