Article: Data on Tay-Sachs disease discussed by D. Elstein and colleagues.(Report)

"Objectives To test neurocognitive function in patients with late-onset Tay-Sachs disease (LOTS) using a computerized system to assess whether cognition is a clinically relevant outcome measure of possible therapeutic intervention in LOTS. Ten adults with Tay-Sachs disease were administered at least one battery of the Mindstreams Neurotrax system for evaluation of cognitive function," scientists writing in the Journal of Inherited Metabolic Disease report (see also Tay-Sachs Disease).

"Six sub-scores and a Global Cognitive Score (GCS) were tabulated. A disease specific severity score was also devised with six domains. Despite identical genotypes, all patients ...

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