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Article: Researchers at State University of New York, New York State Department of Health release new data on flavivirus therapy.
- Article from:
- Virus Weekly
- Article date:
- November 4, 2008
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Investigators publish new data in the report 'Flavivirus methyltransferase: a novel antiviral target.' "Many flaviviruses are significant human pathogens. No effective antiviral therapy is currently available for treatment of flavivirus infections," researchers in the United States report (see also Flavivirus Therapy).
"Development of antiviral treatment against these viruses is urgently needed. The flavivirus methyltransferase (MTase) responsible for N-7 and 2'-O methylation of the viral RNA cap has recently been mapped to the N-terminal region of nonstructural protein 5. Structural and functional studies suggest that the MTase represents a novel antiviral ...