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Article: Phytochemical composition and in vitro pharmacological activity of two rose hip (Rosa canina L.) preparations.(Report)
- Article from:
- Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
- Article date:
- October 1, 2008
- Author:
CopyrightCOPYRIGHT 2008 Urban & Fischer Verlag. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Abstract
The aim of the present study was to compare powdered rose hip with and without fruits (Rosa pseudofructus cum/sine fructibus, Rosa canina L., Rosaceae) with regard to their phytochemical profile and their in vitro antiinflammatory and radical-scavenging properties. The two powders were subsequently extracted with solvents of increasing polarity and tested for inhibition of cyclooxygenase (COX-1, COX-2) and of 5-LOX-mediated leukotriene [B.sub.4] (LT[B.sub.4]) formation as well as for DPPH-radical-scavenging capacity. While the water and methanol extracts were inactive in the COX-1, COX-2 and LT[B.sub.4] inhibition assays, the n-hexane and the ...