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Article: Medical School, Department of Otorhinolaryngology details research in nasal polyps.
- Article from:
- Biotech Week
- Article date:
- November 19, 2008
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Researchers detail in 'Toll-like receptor 2, 3, 4, 5 ligands and interleukin-4 synergistically induce TARC production in nasal polyp fibroblasts,' new data in nasal polyps. "Although type 2 T helper (Th2) cytokines such as IL-4 and IL-5 play a crucial role in the pathogenesis of chronic sinusitis with allergy, the mechanism underlying the predominance of Th2 cytokines has yet to be clarified. Thymus and activation-regulated chemokine (TARC) has been known to facilitate the recruitment of Th2 polarized cells, resulting in high levels of Th2 cytokines in the sinus mucosa as well as nasal polyps," scientists in Tokyo, Japan report (see also Nasal Polyps).
"The nasal ...