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Article: Nevirapine regimen reduces risk of HIV transmission from breast-feeding--at least in the short term.(DIGESTS)(Clinical report)
- Article from:
- International Family Planning Perspectives
- Article date:
- September 1, 2008
- Author:
CopyrightCOPYRIGHT 2008 Guttmacher Institute. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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A six-week postpartum regimen of the anti-retroviral drug nevirapine reduces HIV transmission from breast-feeding in the short term, but the benefits are no longer apparent after six months, according to findings from three coordinated randomized trials conducted in Ethiopia, India and Uganda. (1) Among infants who were HIV-negative a week after birth, those who received nevirapine for six weeks--an initial dose followed seven days later by five weeks of daily doses--were less likely than those who received a single dose of the drug at birth to have HIV at the end of treatment (odds ratio, 0.5). At the six-month follow-up, the difference in HIV rates was no longer ...