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Article: Pulmonary bacterial pathogens in cystic fibrosis patients and antibiotic therapy: a tool for the health workers.(Review)(Clinical report)
- Article from:
- International Archives of Medicine
- Article date:
- November 7, 2008
- Author:
CopyrightCOPYRIGHT 2008 BioMed Central Ltd. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Authors: Henrique Douglas M Coutinho (corresponding author) [1]; Vivyanne S Falc
ão-Silva [2]; Gregório Fernandes Gonçalves [2]
Introduction
Cystic fibrosis (CF) is the most common autosomal genetic disease in North America, affecting 1:2000 Caucasian individuals [1]. This disease is caused by mutations affecting the cystic fibrosis conductance regulator protein (CFTR) and is characterized by chronic lung malfunction, pancreatic insufficiency and high levels of chloride in sweat. Its high mortality index is evident when lung and spleen are affected, but other organs can also be affected. The persons affected die ...
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