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Article: RLS may be a neurodevelopmental disorder.(Neurology)(restless legs syndrome)(Disease/Disorder overview)
- Article from:
- Internal Medicine News
- Article date:
- October 15, 2008
- Author:
CopyrightCOPYRIGHT 2008 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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CHICAGO -- German researchers have identified a fourth genetic risk variant for restless legs syndrome.
The PTPRD gene located on chromosome 9 joins a newly minted list of common risk variants found to be associated with the disorder. Carriers of one risk allele have a 50% increased risk of developing restless legs syndrome (RLS), Dr. Juliane Winkelmann said at the 12th International Congress of Parkinson's Disease and Movement Disorders.
Moreover, two of the four genes where the variants are located are clearly involved in early embryogenesis, suggesting that RLS may be a developmental disorder.
"It's possible that minor alterations of spinal ...