Article: Black box on efalizumab's label warns of infection risk.(Skin Disorders)

Article: Patients dropping efalizumab face ...
Internal Medicine News;  April 1, 2009 ;     700+ words ... ... in switching patients from efalizumab to another medication without ... old German who had been on efalizumab for 3.2 years. In contrast ... years. They too had been on efalizumab for longer than 3 years ... Drug Administration-ordered black box warning. PML is a demyelinating ...

Article: Efalizumab gets boxed warning after serious infections ...
Skin & Allergy News;  November 1, 2008 ;     700+ words ... ... label of the immunomodulator efalizumab will soon have a black box warning describing the potential ... infections as risks associated with efalizumab (Raptiva). The FDA has ... Genentech, the manufacturer of efalizumab, submit plans for a risk ...

Article: Efalizumab efficiency
Dermatology Times;  April 1, 2003 ;     700+ words ...Ongoing efalizumab controls psoriasis safely for majority ... support the efficacy and safety of efalizumab (Raptiva), the humanized CD-1 ... the clinical development program that efalizumab would be a chronic treatment for psoriasis ...

Article: Efalizumab may be next biologic agent for psoriasis: FDA ...
Internal Medicine News;  November 1, 2003 ;     700+ words ... ... GAITHERSBURG, MD. -- The biologic agent efalizumab has earned a federal advisory panel ... risk/benefit ratio for the use of efalizumab in treating psoriasis was favorable ... best way to transition patients off efalizumab when indicated. In four randomized ...

Article: Extended efalizumab therapy sustains efficacy without ...
Journal of Drugs in Dermatology;  November 1, 2004 ;     700+ words ... ... the safety and efficacy of extended efalizumab therapy, 339 patients with moderate ... received 2 mg/kg subcutaneous (SC) efalizumab weekly for 12 weeks. At Week 12, 290 ... maintenance treatment with weekly SC efalizumab. At Week 12, 82%, 41%, and 13 ...

Article: Rebound of psoriasis after efalizumab discontinuation, ...
Journal of Drugs in Dermatology;  September 1, 2007 ;     700+ words ...Abstract Psoriasis rebound after efalizumab discontinuation is well-documented ... experienced psoriasis rebound 2 months after efalizumab discontinuation, despite being on more ... therapy were not sufficient to prevent efalizumab-associated rebound. In addition to ...

Article: When to consider using efalizumab for ...
Skin & Allergy News;  May 1, 2008 ;     700+ words ... ... but in certain situations he prefers efalizumab. At the annual Hawaii dermatology seminar ... he gave his top six reasons for using efalizumab for psoriasis: * Severe scalp psoriasis ... be highly distressing for patients. Efalizumab (Raptiva) brings about rapid improvement ...