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Article: Calcineurin inhibitors may speed MF progression.(Cutaneous Oncology)
- Article from:
- Skin & Allergy News
- Article date:
- August 1, 2008
- Author:
CopyrightCOPYRIGHT 2008 International Medical News Group. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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KYOTO, JAPAN -- Topical calcineurin inhibitors should be used with caution when a diagnosis of atopic dermatitis is less than certain because they might accelerate progression of early-stage mycosis fungoides, often clinically indistinguishable from the atopic disorder.
"Biopsies should be obtained before using them on infiltrated facial lesions, which could be folliculotropic mycosis fungoides," Grace C. Sun advised at an international investigative dermatology meeting.
Because both the symptoms and skin biopsy findings are often nonspecific in early mycosis fungoides, many affected patients are misdiagnosed as having other skin diseases--particularly ...