Article: Research from McMaster University provide new insights into physiology.

Fresh data on physiology are presented in the report 'LXR-induced reverse cholesterol transport in human airway smooth muscle is mediated exclusively by ABCA1.' According to recent research from Hamilton, Canada, "The association of hypercholesterolemia and obesity with airway hyperresponsiveness has drawn increasing attention to the potential role of cholesterol and lipid homeostasis in lung physiology and in chronic pulmonary diseases such as asthma. We have recently shown that activation of the nuclear hormone receptor liver X receptor (LXR) stimulates cholesterol efflux in human airway smooth muscle (hASM) cells and induces expression of the ATP-binding cassette (ABC) ...

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