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Article: Children's Hospital study demonstrates how bone marrow transplant can cure sickle cell disease.
- Article from:
- Pediatrics Week
- Article date:
- November 29, 2008
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A unique approach to bone marrow transplantation pioneered in part by a Children's Hospital of Pittsburgh of UPMC physician has proven to be the only safe and effective cure for sickle cell disease, according to a new study.
Lakshmanan Krishnamurti, MD, a pediatric hematologist/oncologist at Children's Hospital, helped pioneer a form of bone marrow transplantation which relies on reduced-intensity conditioning (RIC). RIC regimens are less toxic to patients and therefore can be offered to patients with severe sickle cell disease because they eliminate life-threatening side effects generally associated with bone marrow transplantation.
In a study ...