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Article: Study findings from E.K. Dirican et al broaden understanding of assisted reproduction.(Report)
- Article from:
- Biotech Week
- Article date:
- December 3, 2008
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According to recent research published in the Journal of Assisted Reproduction and Genetics, " Magnetic activated cell sorting (MACS) eliminates apoptotic spermatozoa based on the presence of externalized phosphatidylserine residues. We evaluated the outcome of male fertility treatment when intracytoplasmic sperm injection (ICSI) into human oocytes was performed with non-apoptotic MACS-selected spermatozoa."
"Methods 196 couples were treated by ICSI following spermatozoa preparation by MACS (study group; 122 couples) or density gradient centrifugation (DGC) (control group; 74 couples). Fertilization, cleavage, pregnancy, and implantation rates were analyzed. ...