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Article: New obstetrics study findings reported from F. Yarandi and co-authors.
- Article from:
- Women's Health Weekly
- Article date:
- December 18, 2008
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In this recent study, researchers in Iran conducted a study "To compare the efficacy of methotrexate and actinomycin D as single agents in first-line chemotherapy for women with low-risk gestational trophoblastic neoplasia (LR-GTN). A total of 131 women with LR-GTN were randomized to receive a weekly pulsed dose of 30 mg/m(2) Of methotrexate intramuscularly (n = 81) or a pulsed intravenous bolus of 1.25 mg/m(2) of actinomycin D every 2 weeks (n = 50)."
"An additional cycle was administered as consolidation treatment following normalization of the serum level of beta-human chorionic gonadotropin (
The researchers concluded: "Actinomycin D may be a better option ...