Article: Hyperthermic intraoperative intraperitoneal chemotherapy safety considerations.

Exposures to infectious diseases, residual ethylene oxide, radiation, and inadvertent inhalation of anesthetics are familiar occupational risks to perioperative staff members. As more surgeons use hyperthermic intraoperative intraperitoneal chemotherapy (HIIC) to treat patients with abdominopelvic cavity malignancies, perioperative staff members face increasing risks of exposure to cytotoxic agents. The cumulative effects of long-term, low-dose occupational exposure to cytotoxic agents are unknown. Clinical research results offer few answers to questions about cumulative effects, because research protocols are designed to study the toxicities of cytotoxic agents ...

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