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Article: Decreased activity of basal ganglia is the main cause of abnormal muscle constrictions in dystonia.
- Article from:
- NewsRx Health
- Article date:
- January 4, 2009
CopyrightCOPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Dystonia is a neurological disorder characterized by involuntary abnormal muscle constrictions. More than 300,000 people in North America are affected, but the mechanism of abnormal muscle constrictions has not been well understood. Here, Japanese research team led by Prof Atsushi Nambu and Dr Satomi Chiken of National Institute for Physiological Sciences (NIPS) in Japan, with Dr. Pullanipally Shashidharan of Mt Sinai School of Medicine in USA, has found that the decreased activity of the basal ganglia, a part of the brain structure, is the main cause of abnormal muscle constrictions of dystonia using a mouse model. They report their findings in Journal of Neuroscience, on ...
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