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Article: Researchers from University of North Carolina report recent findings in heredity.
- Article from:
- Genomics & Genetics Weekly
- Article date:
- January 9, 2009
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According to recent research from the United States, "Genomic imprinting refers to the pattern of monoallelic parent-of-origin-dependent gene expression where one of the two alleles at a locus is expressed and the other silenced. Although some genes in mice are known to be imprinted, the true scope of imprinting and its impact on the genetic architecture of a wide range of morphometric traits is mostly unknown."
"We therefore searched for quantitative trait loci (QTL) exhibiting imprinting effects on mandible size and shape traits in a large F-3 population of mice originating from an intercross of the LG/J (Large) and SM/J (Small) inbred strains. We discovered a ...