Article: Reports from University of Copenhagen describe recent advances in obesity.

According to recent research from Frederiksberg, Denmark, " Weight-loss drugs produce an additional mean weight loss of only 3-5 kg above that of diet arid placebo over 6 months, and more effective pharmacotherapy of obesity is needed. We assessed the efficacy and safety of tesofensine-an inhibitor of the presynaptic uptake of noradrenaline, dopamine, and serotonin-in patients with obesity."

" We undertook a phase II, randomised, double-blind, placebo-co n trolled trial in five Danish obesity management centres. After a 2 week run-in phase, 203 obese patients (body-mass index 30-

The researchers concluded: "Funding Neurosearch A/S, Denmark."

Astrup and ...

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