Article: CKD increases risk for cardiovascular events.(Nephrology)(chronic kidney disease)

PHILADELPHIA--Hypertensive patients with chronic kidney disease were significantly more likely to experience cardiovascular events than were those with normal renal function, but amlodipine-based treatment may have slowed chronic kidney disease progression in stage 3 patients, according to subanalysis of the large ACCOMPLISH trial.

The Avoiding Cardiovascular Events Through Combination Therapy in Patients Living With Systolic Hypertension (ACCOMPLISH) trial randomized 11,506 hypertensive patients to receive the angiotensin-converting enzyme inhibitor benazepril plus the calcium channel blocker amlodipine, or benezepril plus the diuretic hydrochlorothiazide, said ...

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