Article: Evidence of maternal-fetal transmission of Parachlamydia acanthamoebae.(LETTERS)(Clinical report)

To the Editor: Parachlamydia acanthamoebae is a recently identified agent of pneumonia (1-3) and has been linked to adverse pregnancy outcomes, including human miscarriage and bovine abortion (4,5). Parachlamydial sequences have also been detected in human cervical smears (4) and in guinea pig inclusion conjunctivitis (6). We present direct evidence of maternal--fetal transmission of P acanthamoebae.

We tested 78 amniotic fluid samples from patients who delivered prematurely (defined as spontaneous delivery before 37 weeks of gestation) at the Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland, from 2003 to 2006. DNA was extracted by using the ...

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