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Article: Increased expression of lipocalin-type prostaglandin D.sub.2 synthase in osteoarthritic cartilage.(Research article)(Report)
- Article from:
- Arthritis Research & Therapy
- Article date:
- December 18, 2008
- Author:
CopyrightCOPYRIGHT 2008 BioMed Central Ltd. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Authors: Nadia Zayed [1]; Xinfang Li [1]; Nadir Chabane [1]; Mohamed Benderdour [2]; Johanne Martel-Pelletier [1]; Jean-Pierre Pelletier [1]; Nicolas Duval [3]; Hassan Fahmi (corresponding author) [1]
Introduction
Osteoarthritis (OA) is the most common joint disorder and is a leading cause of disability throughout the world [1]. It can cause pain, stiffness, swelling, and loss of function in the joints. Pathologically, OA is characterized by progressive degeneration of articular cartilage, synovial inflammation, and subchondral bone remodeling. These processes are thought to be largely mediated through excess production of proinflammatory and ...
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