Article: Getting a head in frog development. (The Future of Aquatic Research in Space: Neurobiology, Cellular and Molecular Physiology)

The development of a head in frog embryos depends on the vegetal cortex of the egg. This at first seems odd because the head develops on the opposite side of the egg, close to the animal cortex. Nonetheless, the vegetal cortex not only is the repository of interesting localized RNAs, but it also causes the cytoplasmic movement that initiates a chain of events, culminating in the head.

During oogenesis, RNAs are specifically transported to the vegetal cortex (Forristall et al., 1995; Kloc and Etkin, 1995). These RNAs are of two types. One type is involved in formation of germ cells and the other in formation of the head and other dorsoanterior structures. Germ cells ...

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