Article: Should digestion assays be used to estimate persistence of potential allergens in tests for safety of novel food proteins?(Review)(Report)

Authors: Santiago Schnell (corresponding author) [1]; Rod A Herman [2]

Background

The adult human gastrointestinal tract (GI) is a tube approximately 9 meters long, running through the body from the mouth to the anus. The lumen of the GI tract is continuous with the external environment, keeping its contents outside of the rest of the body. The epithelial layer, which lines the interior of the GI tract, presents a partial barrier to invasion by ingested pathogens, parasites, toxins and antinutrients. If pathogens, toxins and food proteins breach the epithelium barrier, the immune system acts as our primary defense system. Antibodies are formed that ...

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