|
|
Article: Sensitization of ovarian cancer cells to cisplatin by genistein: the role of NF-kappaB.(Research)(Clinical report)
- Article from:
- Journal of Ovarian Research
- Article date:
- November 24, 2008
- Author:
CopyrightCOPYRIGHT 2008 BioMed Central Ltd. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
|
Authors: Leigh A Solomon [1]; Shadan Ali [2]; Sanjeev Banerjee [3]; Adnan R Munkarah [4]; Robert T Morris [1]; Fazlul H Sarkar (corresponding author) [3]
Background
There will be an estimated 15,520 deaths from ovarian carcinoma and 21,650 new cases diagnosed in 2008 [1]. Unfortunately, at the time of diagnosis the majority of patients will have disseminated disease. Resistance to platinum-containing regimens and tumor heterogeneity confers a poor prognosis in patients with epithelial ovarian cancer. Platinum-resistance is a complex issue and is currently believed to be associated with an unstable phenotype of ovarian cancer cells that are believed ...
Related newspaper, magazine, and journal articles:
|