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Article: Inhaled drugs to reduce exacerbations in patients with chronic obstructive pulmonary disease: a network meta-analysis.(Research article)(Report)
- Article from:
- BMC Medicine
- Article date:
- January 14, 2009
- Author:
CopyrightCOPYRIGHT 2009 BioMed Central Ltd. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Authors: Milo A Puhan (corresponding author) [1,2]; Lucas M Bachmann [1]; Jos Kleijnen [3]; Gerben ter Riet [4]; Alphons G Kessels [5]
Background
Chronic obstructive pulmonary disease (COPD) has become a leading cause of death worldwide and its management requires an enormous amount of human and financial resources [1, 2]. Reduction of exacerbation rates is one of the main treatment goals in COPD management since exacerbations bear heavily on the patient's health-related quality of life and prognosis as well as on COPD-related costs [3]. Several conventional meta-analyses provided evidence that long-acting beta-agonists, long-acting ...
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