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Article: Stability of multiple alignments and phylogenetic trees: an analysis of ABC-transporter proteins family.(Short report)(Report)
- Article from:
- Algorithms for Molecular Biology
- Article date:
- November 6, 2008
- Author:
CopyrightCOPYRIGHT 2008 BioMed Central Ltd. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Authors: Holger Wagner [1]; Burkhard Morgenstern (corresponding author) [2]; Andreas Dress [3,4]
1 Introduction
For more than three decades, sequence-based computer programs for phylogenetic reconstruction are routinely used for sequence-data analysis, see [10, 34, 11] for reviews of various popular methods. They are crucial tools not only for understanding gene and species evolution, but also for analyzing the structure and function of proteins. A good example is the family of ABC-transporter proteins that became a topic of active research during the last few years (ABC stands for ATP-Binding Casette). At present, thousands of different ABC ...
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