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Article: Studies from S.L. Macdonald et al further understanding of stem cell research.
- Article from:
- Biotech Week
- Article date:
- February 18, 2009
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According to recent research published in the journal Biochemical Society Transactions, "MBL (mannan-binding lectin; also called mannose-binding lectin) is a circulating C-type lectin with a collagen like region synthesized mainly by the liver. MBL may influence susceptibility to infection in recipients of stem cell transplants, and it has even been suggested that the MBL status of a donor can influence the recipient's susceptibility to post-transplant infections."
"We have previously reported that MBL can be detected on human monocytes and monocyte-derived dendritic cells, based on detection using biotinylated anti-MBL, suggesting that those cells could ...