Article: New inflammation study findings have been published by S.A. Boehme and colleagues.

"A FITC-induced allergic contact hypersensitivity model was used to investigate the role that the prostaglandin D-2 receptor-chemoattractant receptor-homologous molecule expressed on T(h)2 cells (CRTH2) plays in modulating cutaneous inflammation. Our results show that inhibition of CRTH2, achieved via administration of a potent, small molecule antagonist, Compound A (Cmpd A), effectively blocked edema formation and greatly reduced the inflammatory infiltrate and skin pathology observed in drug vehicle-treated animals," scientists writing in the journal International Immunology report (see also Inflammation).

"Gene expression analysis revealed that Cmpd A ...

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