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Article: University of Rostock details research in liver failure.
- Article from:
- Blood Weekly
- Article date:
- February 26, 2009
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According to recent research from Rostock, Germany, "Liver injury and cell death are prominent features in the pathogenesis of acute liver failure. Mitochondrial uncoupling protein 2 plays a controversial role in liver cell death through its involvement in the production of reactive oxygen species and adenosine triphosphate."
"This randomized controlled animal study was designed to investigate the exact role of uncoupling protein 2 in the pathogenesis of endotoxemic acute liver failure. Research laboratory of an academic institution. Interventions, and Measurements: Uncoupling protein 2+/+ and uncoupling protein 2-/- mice were challenged with D-galactosamine ...