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Article: Survey of metabolites finds new prostate cancer marker.
- Article from:
- Drug Week
- Article date:
- February 27, 2009
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Howard Hughes Medical Institute researchers have identified a new biological marker present in the urine of patients with prostate cancer that indicates whether the cancer is progressing and spreading (see also Howard Hughes Medical Institute).
In experiments reported in the February 12, 2009, issue of the journal Nature, the scientists identified 10 metabolites that become more abundant in prostate cells as cancer progresses. Their studies showed that one of these chemicals, sarcosine, helps prostate cancer cells invade surrounding tissue.
HHMI investigator Arul Chinnaiyan and colleagues at the University of Michigan showed that as prostate cancer ...