Article: Mapping of IgE-binding regions on recombinant Cyn d 1, a major allergen from Bermuda Grass Pollen (BGP).(Research)(Report)

Authors: Ruby Tiwari [1,2]; Prem L Bhalla [1]; Mohan B Singh (corresponding author) [1]

Background

It is estimated that up to 20% of the population in developed countries suffers from atopic diseases caused by airborne allergens derived from grass and tree pollen, house dust mites and animal dander, which has a significant impact on quality of life and economic consequences [1, 2]. The role of grass pollen allergens in triggering immunoglobulin E (IgE)-mediated type I allergic diseases, such as allergic rhinitis, conjunctivitis, and bronchial asthma is very well established [3, 4]. Epidemiologic studies have revealed that allergies to Bermuda grass (

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