Article: House dust mite allergens (Der p I and Der p V) within domestic environments of atopic and control children.

IN AN EPIDEMIOLOGICAL STUDY, the prevalence of asthma in schoolchildren in Taipei reportedly increased from 1.3% in 1974 to 5.1% in 1985 and to 10.8% in 1994 (unpublished data). Anti-mite immunoglobulin E (IgE) sera from allergic patients in Taiwan reacted with several components. More than 90% of the allergic asthmatic children in Taiwan reacted with the two well-characterized major allergens, Der p I and Der p II, and approximately 60% of these children reacted with a newly characterized low-molecular-weight allergein, Der p V.[1] Interestingly, although Der p V reacted with only 60% of allergic patient studies, IgE reactivity appeared to be stronger than that of ...

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