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Article: Activated mammalian target of rapamycin is associated with T regulatory cell insufficiency in nasal polyps.(Research)(Report)
- Article from:
- Respiratory Research
- Article date:
- February 27, 2009
- Author:
CopyrightCOPYRIGHT 2009 BioMed Central Ltd. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Authors: Geng Xu [1]; Jiahong Xia [2]; Xiaoyang Hua [2]; Han Zhou [3]; Chuanzhao Yu [3]; Zheng Liu [2]; Kemin Cai [3]; Jianbo Shi [1]; Huabin Li (corresponding author) [1,3]
Background
Chronic rhinosinusitis is generally classified as chronic rhinosinusitis without nasal polyps (CRSnNP) or with nasal polyps (CRSwNP) [1]. CRSwNP is characterized by polyp formation and mixed types of Th1/Th2 infiltrates and their corresponding cytokine secretions [2, 3]. There is also evidence that CRSwNP display a Th2-skewed inflammatory response with high levels of IL-5 and IgE [4]. At present, an imbalanced Th1/Th2 network is thought to play a critical role in the ...
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Article: Scientists at Capital University target nasal ...
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... ... i>, The pathogenesis of nasal polyps still is not clear. This disease is ... expression of the survivin gene in human nasal polyps. We investigated the expression of survivin in nasal polyps of adult patients with chronic rhinosinusitis ...
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