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Article: Reports summarize nasal polyps research from S. Lo and co-authors.(Report)
- Article from:
- Biotech Week
- Article date:
- March 11, 2009
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"Carbon monoxide is an endogenous vasodilator gas produced by the enzyme heme oxygenase (HO). HO is expressed in human nasal mucosa, but its pathophysiological role in nasal inflammatory diseases is not fully understood," researchers in Farnborough, the United Kingdom report (see also Nasal Polyps).
"The aim of this study was to detect and compare the expression of HO-1 and -2 isoforms in nasal polyps with normal nasal mucosa. Immunohistochemical analysis using antibodies specific for HO-1 and -2 was conducted on nasal polyps from nine patients with allergic nasal polyposis, and on normal nasal mucosa from six controls. Intense HO-1 immunoreactivity was observed ...