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Article: Hypothetical Pneumocystis jirovecii transmission from immunocompetent carriers to infant.(LETTERS)
- Article from:
- Emerging Infectious Diseases
- Article date:
- March 1, 2009
- Author:
CopyrightCOPYRIGHT 2009 U.S. National Center for Infectious Diseases. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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To the Editor: The recent dispatch article by Rivero et al. reports the transmission of Pneumocystis jirovecii from immunocompetent grandparents to their granddaughter (1). The authors' conclusion was based on 2 facts: the grandparents were carriers but neither the parents nor the child's brother was a carrier, and the P. jirovecii genotype observed in the grandparents was identical to that found in the infant. In our opinion, the data provided by the authors do not support the conclusion that transmission has occurred. First, the 2 markers used for typing show a small number of alleles and thus provide low discrimination among isolates (2). Consequently, the P. jirovecii ...