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Article: New findings from University of Nottingham describe advances in life sciences.
- Article from:
- Biotech Week
- Article date:
- March 25, 2009
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Data detailed in 'Enhanced latent inhibition in dopamine receptor-deficient mice is sex-specific for the D1 but not D2 receptor subtype: implications for antipsychotic drug action' have been presented. According to recent research from Nottingham, the United Kingdom, "Latent inhibition (LI) is reduced learning to a stimulus that has previously been experienced without consequence. It is an important model of abnormal allocation of salience to irrelevant information in patients with schizophrenia."
"In rodents LI is abolished by psychotomimetic drugs and in experimental conditions where LI is low in controls, its expression is enhanced by antipsychotic drugs with ...