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Article: New findings reported from Montreal Children's Hospital describe advances in life sciences.
- Article from:
- Biotech Week
- Article date:
- April 8, 2009
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According to a study from Montreal, Canada, "Phenylketonuria (PKU), a Mendelian autosomal recessive phenotype (OMIM 261600), is an inborn error of metabolism that can result in impaired postnatal cognitive development."
"The phenotypic outcome is multifactorial in origin, based both in nature, the mutations in the gene encoding the L-phenylalanine hydroxylase enzyme, and nurture, the nutritional experience introducing L-phenylalanine into the diet. The PKU story contains many messages including a framework to appreciate the complexity of this disease where phenotype reflects both locus-specific and genomic components," wrote C.N. Sarkissian and colleagues, ...