|
|
Article: Research conducted at Stanford University has provided new information about endocytosis.
- Article from:
- Blood Weekly
- Article date:
- April 16, 2009
CopyrightCOPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
|
"The endocytosis of AMPA receptors (AMPARs) underlies several forms of synaptic plasticity, including NMDA receptor (NMDAR)-dependent long-term depression (LTD), but the molecular mechanisms responsible for this trafficking remain unknown. We found that PSD-95, a major postsynaptic density protein, is important for NMDAR-triggered endocytosis of synaptic AMPARs in rat neuron cultures because of its binding to A kinase-anchoring protein 150 (AKAP150), a scaffold for specific protein kinases and phosphatases," investigators in the United States report (see also Endocytosis).
"Knockdown of PSD-95 with shRNA blocked NMDAR-triggered, but not constitutive or ...
Related newspaper, magazine, and journal articles:
|
|
Article: Nature Neuroscience.(fetal tissue transplants for ...
Alberta Report;
December 6, 1999 ;
621 words
... ... declared that the study published in the December issue of Nature Neuroscience "clearly demonstrates that grafting foetal cells onto ... While enthusiastic, an accompanying paper in the same Nature Neuroscience issue by Roger Barker and Stephen Dunnett of the Centre ...
|
|