Article: Studies from A. Wisniewski et al provide new data on asthma.(Report)

"Allergic asthma is a complex genetic disorder that involves interactions between genetic and environmental factors. Some studies have indicated that transforming growth factor beta(1) (TGF-beta(1)), a pleiotropic cytokine regulating inflammatory reactions and airway remodeling, may participate in the pathogenesis of asthma," scientists in Wroclaw, Poland report (see also Asthma).

"Several polymorphisms have been described in the TGFB1 gene; some were tested in allergic asthma, with conflicting results. The aim of this study was to investigate the possible associations of four TGFB1 gene polymorphisms (-800G > A, -509C > T, 869T > C, and 915G > C) with allergic ...

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