Article: A matching law analysis of the effect of amphetamine on responding reinforced by the opportunity to run.

"Runner's high" is a phenomenon that is widely known but poorly understood. The pharmacological basis of this phenomenon has been attributed to a release of endogenous opiates that occurs with intense exercise (Thoren, Floras, Hoffmann, & Seals, 1990); however, evidence in support of this opiate hypothesis is less than substantial (Steinberg & Sykes, 1985). An alternative, lesser known hypothesis is that the pharmacological basis of the rewarding effect of running is dopaminergic (Lambert, 1992). According to this hypothesis, running produces an increase in the release of dopamine in the mesolimbic pathway that is associated with the biological basis of reward (Lambert, ...

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