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Article: The effect of using a powered toothbrush on MCP-1 and RANTES levels in patients with gingivitis.
- Article from:
- Journal of Dental Hygiene
- Article date:
- September 22, 2008
- Author:
CopyrightCOPYRIGHT 2008 American Dental Hygienists' Association. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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The purpose of this pilot study was to investigate if a powered toothbrush significantly reduced the concentration of MCP-1 and RANTES over time in a gingivitis group when compared to a manual toothbrush. MCP-1 and RANTES are pro-inflammatory cytokines that are expressed in gingival crevicular fluid of patients with gingival inflammation.
This study looked at the levels of these cytokines as indicators for a reduction in the host inflammatory and immune response.
Twenty gingivitis patients, 18-65 years of age with pocket depths [less than or equal to]6mm and a minimum of 10% bleeding upon probing were enrolled in this IRB approved pilot study. ...