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Article: New lymphoma research has been reported by S. Berentsen et al.
- Article from:
- Blood Weekly
- Article date:
- May 21, 2009
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"Recent data on the close association between chronic cold agglutinin disease (CAD) and Waldenstrom's macroglobulinemia (WM) have provided a new potential for therapeutic achievements. In 90% of patients with CAD, the cold agglutinins are monoclonal immunoglobulin M kappa antibodies and clonal lymphocytes can be detected by flow cytometry of bone marrow aspirates," scientists in Haugesund, Norway report (see also Lymphoma).
"Bone marrow lymphoplasmacytic lymphoma is found by histology and immune histochemistry in 50% of the patients. Thus, CAD represents a spectrum of clonal lymphoproliferative disorders overlapping with WM. Conventional therapies are ...